Chemicals and Drugs

Interleukin-33

A member of the INTERLEUKIN-1 protein family involved in the maturation of TH2 CELLS and the activation of MAST CELLS; BASOPHILS; EOSINOPHILS and NK CELLS. It is also produced by ENDOTHELIAL CELLS; EPITHELIAL CELLS and FIBROBLASTS; where it can function as an alarmin to modulate immune and inflammatory responses to tissue damage.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A member of the INTERLEUKIN-1 protein family involved in the maturation of TH2 CELLS and the activation of MAST CELLS; BASOPHILS; EOSINOPHILS and NK CELLS. It is also produced by ENDOTHELIAL CELLS; EPITHELIAL CELLS and FIBROBLASTS; where it can function as an alarmin to modulate immune and inflammatory responses to tissue damage.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

3 entry terms
  • IL-33
  • IL33
  • Interleukin 33

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2016 (2005)

MeSH Record

Previous Indexing

  • Interleukins (2005-2015)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Interleukin-33. Medical Subject Headings (MeSH). 2026. Unique ID D000067596. http://id.nlm.nih.gov/mesh/2026/D000067596
  2. Interleukin-33. In: Wikidata. https://www.wikidata.org/wiki/Q24774217