Chemicals and Drugs

Interferon gamma Receptor

A heterodimeric receptor composed of two subunits IFNGR1 and IFNGR2. Activated IFNGR1 subunit is believed to form a docking site for SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1 (STAT1). IFNGR2 associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A heterodimeric receptor composed of two subunits IFNGR1 and IFNGR2. Activated IFNGR1 subunit is believed to form a docking site for SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1 (STAT1). IFNGR2 associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG).

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Classification

Broader headings

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MeSH Record

Synonyms

18 entry terms
  • CD119 Antigen
  • CDw119 Antigen
  • IFN-gamma Receptor 1
  • IFN-gammaR
  • IFNGR2 Protein
  • Interferon gamma Receptor 2
  • Interferon gamma Receptors
  • Receptor, Interferon gamma
  • 1, IFN-gamma Receptor
  • Antigen, CD119
  • Antigen, CDw119
  • IFN gamma Receptor 1
  • IFN gammaR
  • Protein, IFNGR2
  • Receptor 1, IFN-gamma
  • Receptors, Interferon gamma
  • gamma Receptor, Interferon
  • gamma Receptors, Interferon

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2024 (1993)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Interferon gamma Receptor. Medical Subject Headings (MeSH). 2026. Unique ID D000096743. http://id.nlm.nih.gov/mesh/2026/D000096743
  2. Interferon gamma Receptor. In: Wikidata. https://www.wikidata.org/wiki/Q83138044