Structured Summary
Abstract
An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.
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Synonyms
6 entry terms
- IFN-Regulatory Factor 3
- IRF-3 Transcription Factor
- IFN Regulatory Factor 3
- IRF 3 Transcription Factor
- Interferon Regulatory Factor 3
- Transcription Factor, IRF-3
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006(1996)
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AMA Style
References
- National Library of Medicine. Interferon Regulatory Factor-3. Medical Subject Headings (MeSH). 2026. Unique ID D050838. http://id.nlm.nih.gov/mesh/2026/D050838
- Interferon Regulatory Factor-3. In: Wikidata. https://www.wikidata.org/wiki/Q24746065