Chemicals and Drugs

Intercellular Adhesion Molecule-3

A membrane glycoprotein and cell adhesion molecule expressed by LEUKOCYTES that contains multiple Ig-like domains. It is a ligand for LFA-1 (integrin alphaLbeta2) and integrin alpha-D/beta-2. Its interaction with LFA-1 may play a role in the PHAGOCYTOSIS of NEUTROPHILS by MACROPHAGES following APOPTOSIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A membrane glycoprotein and cell adhesion molecule expressed by LEUKOCYTES that contains multiple Ig-like domains. It is a ligand for LFA-1 (integrin alphaLbeta2) and integrin alpha-D/beta-2. Its interaction with LFA-1 may play a role in the PHAGOCYTOSIS of NEUTROPHILS by MACROPHAGES following APOPTOSIS.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

See Also

MeSH Record

Synonyms

9 entry terms
  • Antigens, CD50
  • CD50 Antigen
  • CDw50 Antigen
  • ICAM-3
  • ICAM3
  • Antigen, CD50
  • Antigen, CDw50
  • CD50 Antigens
  • Intercellular Adhesion Molecule 3

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2018

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Intercellular Adhesion Molecule-3. Medical Subject Headings (MeSH). 2026. Unique ID D000074001. http://id.nlm.nih.gov/mesh/2026/D000074001
  2. Intercellular Adhesion Molecule-3. In: Wikipedia. https://en.wikipedia.org/wiki/ICAM3
  3. Intercellular Adhesion Molecule-3. In: Wikidata. https://www.wikidata.org/wiki/Q21157908