Chemicals and Drugs

Integrin beta Chains

Integrin beta chains combine with integrin alpha chains to form heterodimeric cell surface receptors. Integrins have traditionally been classified into functional groups based on the identity of one of three beta chains present in the heterodimer. The beta chain is necessary and sufficient for integrin-dependent signaling. Its short cytoplasmic tail contains sequences critical for inside-out signaling.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Integrin beta chains combine with integrin alpha chains to form heterodimeric cell surface receptors. Integrins have traditionally been classified into functional groups based on the identity of one of three beta chains present in the heterodimer. The beta chain is necessary and sufficient for integrin-dependent signaling. Its short cytoplasmic tail contains sequences critical for inside-out signaling.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

4 entry terms
  • Integrin beta Subunits
  • beta Integrins
  • Integrins, beta
  • beta Chains, Integrin

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2003

MeSH Record

Previous Indexing

  • Integrins (1990-2002)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Integrin beta Chains. Medical Subject Headings (MeSH). 2026. Unique ID D039641. http://id.nlm.nih.gov/mesh/2026/D039641
  2. Integrin beta Chains. In: Wikidata. https://www.wikidata.org/wiki/Q24778538