Chemicals and Drugs

Integrin alphaXbeta2

A major adhesion-associated heterodimer molecule expressed by MONOCYTES; GRANULOCYTES; NK CELLS; and some LYMPHOCYTES. The alpha subunit is the CD11C ANTIGEN, a surface antigen expressed on some myeloid cells. The beta subunit is the CD18 ANTIGEN.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A major adhesion-associated heterodimer molecule expressed by MONOCYTES; GRANULOCYTES; NK CELLS; and some LYMPHOCYTES. The alpha subunit is the CD11C ANTIGEN, a surface antigen expressed on some myeloid cells. The beta subunit is the CD18 ANTIGEN.

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Classification

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Synonyms

18 entry terms
  • Antigen p150,95
  • CR4 Receptor
  • Complement Receptor 4
  • Complement Receptor Type 4
  • Leukocyte Adhesion Protein p150,95
  • Neutrophil GP150
  • Neutrophil Glycoprotein Gp150
  • Receptor, CR4
  • alphaXbeta2 Integrin
  • p150,95 Antigen
  • p150,95 Glycoprotein
  • Antigen, p150,95
  • GP150, Neutrophil
  • Glycoprotein Gp150, Neutrophil
  • Glycoprotein, p150,95
  • Gp150, Neutrophil Glycoprotein
  • Integrin, alphaXbeta2
  • alphaXbeta2, Integrin

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2003 (1991); use INTEGRIN ALPHAXBETA2 (NM) 1985-2002

MeSH Record

Previous Indexing

  • Antigens, Differentiation (1988-1990)
  • Receptors, Leukocyte-Adhesion (1989-1990)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Integrin alphaXbeta2. Medical Subject Headings (MeSH). 2026. Unique ID D016167. http://id.nlm.nih.gov/mesh/2026/D016167
  2. Integrin alphaXbeta2. In: Wikipedia. https://en.wikipedia.org/wiki/Integrin_alphaXbeta2
  3. Integrin alphaXbeta2. In: Wikidata. https://www.wikidata.org/wiki/Q6043298