Structured Summary
Abstract
This integrin alpha subunit combines with INTEGRIN BETA1 to form a receptor (INTEGRIN ALPHA5BETA1) that binds FIBRONECTIN and LAMININ. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds.
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Classification
Broader headings
Related Concepts
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Synonyms
16 entry terms
- Antigens, CD49e
- CD49e Antigen
- CD49e Antigens
- Integrin alphaF
- Platelet Glycoprotein Ic
- VLA-5 alpha Chain
- alpha(5) Integrin
- alpha5 Integrin
- Antigen, CD49e
- Glycoprotein Ic, Platelet
- Ic, Platelet Glycoprotein
- Integrin, alpha5
- VLA 5 alpha Chain
- alpha Chain, VLA-5
- alpha5, Integrin
- alphaF, Integrin
MeSH Record
Aspects Covered
23 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2003 (1996)
MeSH Record
Previous Indexing
- Antigens, CD (1996-2002)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Integrin alpha5. Medical Subject Headings (MeSH). 2026. Unique ID D039482. http://id.nlm.nih.gov/mesh/2026/D039482
- Integrin alpha5. In: Wikipedia. https://en.wikipedia.org/wiki/Integrin_alpha_5
- Integrin alpha5. In: Wikidata. https://www.wikidata.org/wiki/Q21110097