Structured Summary
Abstract
A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is an extrahepatic enzyme that plays a role in metabolism as the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism.
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Classification
Broader headings
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MeSH Record
Synonyms
7 entry terms
- IDO Dioxygenase
- Indolamine-2,3-Dioxygenase
- Indoleamine 2,3-Dioxygenase
- Indoleamine-Oxygen 2,3-Oxidoreductase (Decyclizing)
- Dioxygenase, IDO
- Indolamine 2,3 Dioxygenase
- Indoleamine 2,3 Dioxygenase
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006(1990)
MeSH Record
Previous Indexing
- Dioxygenases (2005)
- Oxygenases (1970-2004)
- Tryptophan Oxygenase (1968-2005)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Indoleamine-Pyrrole 2,3,-Dioxygenase. Medical Subject Headings (MeSH). 2026. Unique ID D050503. http://id.nlm.nih.gov/mesh/2026/D050503
- Indoleamine-Pyrrole 2,3,-Dioxygenase. In: Wikipedia. https://en.wikipedia.org/wiki/Indole_2,3-dioxygenase
- Indoleamine-Pyrrole 2,3,-Dioxygenase. In: Wikidata. https://www.wikidata.org/wiki/Q3785309