Chemicals and Drugs

Indican

A substance occurring in the urine of mammals and also in blood plasma as the normal metabolite of tryptophan. An increased urinary excretion of indican is seen in Hartnup disease from the bacterial degradation of unabsorbed tryptophan.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A substance occurring in the urine of mammals and also in blood plasma as the normal metabolite of tryptophan. An increased urinary excretion of indican is seen in Hartnup disease from the bacterial degradation of unabsorbed tryptophan.

Chemical Identity

Chemical Information

Molecular Formula
C14H17NO6
Molecular Weight
295.29 g/mol
CAS Registry No.
487-60-5
IUPAC Name
(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(1H-indol-3-yloxy)oxane-3,4,5-triol
InChIKey
XVARCVCWNFACQC-RKQHYHRCSA-N
SMILES
C1=CC=C2C(=C1)C(=CN2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O
MeSH Unique ID
D007200
Source
PubChem CID 441564

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

7 entry terms
  • 1H-Indol-3-ol Hydrogen Sulfate Ester
  • Indoxyl Sulfate
  • Sulfate, Indoxyl
  • Indican Monopotassium Salt
  • Indican Monosodium Salt
  • Monopotassium Salt, Indican
  • Monosodium Salt, Indican

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

do not confuse with indican, a glycoside from plants yielding indigo (index under GLYCOSIDES)

MeSH Hierarchy

Tree Number

  1. D03w.633.100.473.393w

AMA Style

References

  1. National Library of Medicine. Indican. Medical Subject Headings (MeSH). 2026. Unique ID D007200. http://id.nlm.nih.gov/mesh/2026/D007200
  2. Indican. In: Wikipedia. https://en.wikipedia.org/wiki/Indican
  3. Indican. In: Wikidata. https://www.wikidata.org/wiki/Q418392
  4. Indican. In: PubChem Compound. CID 441564. https://pubchem.ncbi.nlm.nih.gov/compound/441564