Structured Summary
Abstract
A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome, which has been found to be clinically similar to the human disease. It has been determined that this mouse strain carries a mutation in the fas gene. Also, the MRL/lpr is a useful model to study behavioral and cognitive deficits found in autoimmune diseases and the efficacy of immunosuppressive agents.
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Classification
Broader headings
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Synonyms
6 entry terms
- Mice, Inbred MRL lpr
- Mice, MRL lpr
- Mouse, Inbred MRL lpr
- Mouse, MRL lpr
- MRL lpr Mice
- MRL lpr Mouse
MeSH Record
Aspects Covered
18 allowable subheadings
Indexed with the subheadings abnormalities, anatomy & histology, blood, cerebrospinal fluid, classification, embryology, genetics, growth & development, immunology, injuries, metabolism, microbiology, parasitology, physiology, psychology, surgery, urine, virology.
MeSH Record
Indexing Annotation
NIM with no qualifiers when experimental animal
MeSH Record
History Note
97
MeSH Record
Previous Indexing
- Mice (1981-1996)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Inbred MRL lpr Mice. Medical Subject Headings (MeSH). 2026. Unique ID D019463. http://id.nlm.nih.gov/mesh/2026/D019463
- Inbred MRL lpr Mice. In: Wikidata. https://www.wikidata.org/wiki/Q69375687