Chemicals and Drugs

Impromidine

A highly potent and specific histamine H2 receptor agonist. It has been used diagnostically as a gastric secretion indicator.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A highly potent and specific histamine H2 receptor agonist. It has been used diagnostically as a gastric secretion indicator.

Chemical Identity

Chemical Information

Molecular Formula
C14H23N7S
Molecular Weight
321.45 g/mol
CAS Registry No.
55273-05-7
IUPAC Name
2-[3-(1H-imidazol-5-yl)propyl]-1-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine
InChIKey
MURRAGMMNAYLNA-UHFFFAOYSA-N
SMILES
CC1=C(N=CN1)CSCCNC(=NCCCC2=CN=CN2)N
MeSH Unique ID
D017446
Source
PubChem CID 41376

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • Impromidine Hydrochloride
  • Impromidine Oxalate (1:2)
  • Impromidine Trihydrochloride
  • SK&F-92676
  • SKF-92676
  • Hydrochloride, Impromidine
  • SK&F 92676
  • SK&F92676
  • SKF 92676
  • SKF92676
  • Trihydrochloride, Impromidine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

93; was IMPROMIDINE (NM) 1979-92

MeSH Record

Previous Indexing

  • Guanidines (1979-82,89-1992)
  • Imidazoles (1979-1992)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Impromidine. Medical Subject Headings (MeSH). 2026. Unique ID D017446. http://id.nlm.nih.gov/mesh/2026/D017446
  2. Impromidine. In: Wikipedia. https://en.wikipedia.org/wiki/Impromidine
  3. Impromidine. In: Wikidata. https://www.wikidata.org/wiki/Q6007727
  4. Impromidine. In: PubChem Compound. CID 41376. https://pubchem.ncbi.nlm.nih.gov/compound/41376