Structured Summary
Abstract
Semisynthetic conjugates of various toxic molecules, including RADIOACTIVE ISOTOPES and bacterial or plant toxins, with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; and ANTIGENS. The antitumor or antiviral immune substance carries the toxin to the tumor or infected cell where the toxin exerts its poisonous effect.
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Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
See Also
MeSH Record
Synonyms
57 entry terms
- Affinotoxin
- Affinotoxins
- Antibody-Toxin Conjugate
- Antibody-Toxin Conjugates
- Antibody-Toxin Hybrid
- Antibody-Toxin Hybrids
- Cytotoxin-Antibody Conjugate
- Cytotoxin-Antibody Conjugates
- Immunotoxin
- Monoclonal Antibody-Toxin Conjugate
- Monoclonal Antibody-Toxin Conjugates
- Toxin-Antibody Conjugate
- Toxin-Antibody Conjugates
- Toxin-Antibody Hybrid
- Toxin-Antibody Hybrids
- Antibody Toxin Conjugate
- Antibody Toxin Conjugates
- Antibody Toxin Hybrid
- Antibody Toxin Hybrids
- Antibody-Toxin Conjugate, Monoclonal
- Antibody-Toxin Conjugates, Monoclonal
- Conjugate, Antibody-Toxin
- Conjugate, Cytotoxin-Antibody
- Conjugate, Monoclonal Antibody-Toxin
- Conjugate, Toxin-Antibody
- Conjugates, Antibody-Toxin
- Conjugates, Cytotoxin-Antibody
- Conjugates, Monoclonal Antibody-Toxin
- Conjugates, Toxin-Antibody
- Cytotoxin Antibody Conjugate
- Cytotoxin Antibody Conjugates
- Hybrid, Antibody-Toxin
- Hybrid, Toxin-Antibody
- Hybrids, Antibody-Toxin
- Hybrids, Toxin-Antibody
- Monoclonal Antibody Toxin Conjugate
- Monoclonal Antibody Toxin Conjugates
- Toxin Antibody Conjugate
- Toxin Antibody Conjugates
- Toxin Antibody Hybrid
- Toxin Antibody Hybrids
- Chimeric Toxin
- Chimeric Toxins
- Targeted Toxin
- Targeted Toxins
- Toxin Carrier
- Toxin Carriers
- Toxin Conjugate
- Toxin Conjugates
- Toxins, Chimeric
- Toxins, Targeted
- Carrier, Toxin
- Carriers, Toxin
- Conjugate, Toxin
- Conjugates, Toxin
- Toxin, Chimeric
- Toxin, Targeted
MeSH Record
Aspects Covered
22 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
coordinate IM with specific toxin (IM) + specific immune substance (NIM)
MeSH Record
History Note
90; was ANTIBODY-TOXIN CONJUGATES 1987-89
MeSH Record
Previous Indexing
- Antibodies, Monoclonal (1982-1986)
- Antigens, Surface (1979-1986)
- Antitoxins (1966-1986)
- Cytotoxicity, Immunologic (1978-1986)
- Ricin (1978-1985)
MeSH Hierarchy
Tree Numbers
MeSH Record
NLM Classification
QW 630.5.I3
AMA Style
References
- National Library of Medicine. Immunotoxins. Medical Subject Headings (MeSH). 2026. Unique ID D000922. http://id.nlm.nih.gov/mesh/2026/D000922
- Immunotoxins. In: Wikipedia. https://en.wikipedia.org/wiki/Immunotoxin
- Immunotoxins. In: Wikidata. https://www.wikidata.org/wiki/Q425665