Phenomena and Processes

Immunologic Capping

An energy dependent process following the crosslinking of B CELL ANTIGEN RECEPTORS by multivalent ligands (bivalent anti-antibodies, LECTINS or ANTIGENS), on the B-cell surface. The crosslinked ligand-antigen receptor complexes collect in patches which flow to and aggregate at one pole of the cell to form a large mass - the cap. The caps may then be endocytosed or shed into the environment.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An energy dependent process following the crosslinking of B CELL ANTIGEN RECEPTORS by multivalent ligands (bivalent anti-antibodies, LECTINS or ANTIGENS), on the B-cell surface. The crosslinked ligand-antigen receptor complexes collect in patches which flow to and aggregate at one pole of the cell to form a large mass - the cap. The caps may then be endocytosed or shed into the environment.

MeSH Record

Classification

Broader headings

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See Also

MeSH Record

Synonyms

3 entry terms
  • Capping, Immunologic
  • Immunological Capping
  • Capping, Immunological

MeSH Record

Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

MeSH Record

Indexing Annotation

may appear in the literature as "capping of lymphocytes" or "leukocyte capping"; do not confuse with RECEPTOR CAPPING

MeSH Record

History Note

78

MeSH Record

Previous Indexing

  • Cell Membrane (1966-1977)
  • Lymphocytes (1966-1977)

MeSH Hierarchy

Tree Numbers

  1. G04.774.612
  2. G12.122.612

AMA Style

References

  1. National Library of Medicine. Immunologic Capping. Medical Subject Headings (MeSH). 2026. Unique ID D007152. http://id.nlm.nih.gov/mesh/2026/D007152
  2. Immunologic Capping. In: Wikidata. https://www.wikidata.org/wiki/Q71130180