Structured Summary
Abstract
A 15 kDa joining peptide that forms one of the linkages between monomers of IMMUNOGLOBULIN A or IMMUNOGLOBULIN M in the formation of polymeric immunoglobulins. There is one J chain per one IgA dimer or one IgM pentamer. It is also involved in binding the polymeric immunoglobulins to POLYMERIC IMMUNOGLOBULIN RECEPTOR which is necessary for their transcytosis to the lumen. It is distinguished from the IMMUNOGLOBULIN JOINING REGION which is part of the IMMUNOGLOBULIN VARIABLE REGION of the immunoglobulin light and heavy chains.
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Drug Class
Pharmacological Action
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Synonyms
15 entry terms
- Ig J Chains
- Ig J-Peptide
- Immunoglobulin J Polypeptide
- Immunoglobulin J-Peptide
- J-Chains, Immunoglobulin
- Chains, Ig J
- Ig J Peptide
- Immunoglobulin J Chains
- Immunoglobulin J Peptide
- J Chains, Ig
- J Chains, Immunoglobulin
- J Polypeptide, Immunoglobulin
- J-Peptide, Ig
- J-Peptide, Immunoglobulin
- Polypeptide, Immunoglobulin J
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Aspects Covered
23 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006 (1974)
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AMA Style
References
- National Library of Medicine. Immunoglobulin J-Chains. Medical Subject Headings (MeSH). 2026. Unique ID D007144. http://id.nlm.nih.gov/mesh/2026/D007144
- Immunoglobulin J-Chains. In: Wikidata. https://www.wikidata.org/wiki/Q24774010