Phenomena and Processes

Immune Tolerance

The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.

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Synonyms

3 entry terms
  • Tolerance, Immune
  • Immunosuppression (Physiology)
  • Immunosuppressions (Physiology)

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Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

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Indexing Annotation

do not confuse X ref IMMUNOSUPPRESSION (PHYSIOLOGY) with the Cat E immunol technique IMMUNOSUPPRESSION: Manual 28.21.1

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History Note

66(64)

MeSH Hierarchy

Tree Number

  1. G12.535w.425w

MeSH Record

NLM Classification

QW 920

AMA Style

References

  1. National Library of Medicine. Immune Tolerance. Medical Subject Headings (MeSH). 2026. Unique ID D007108. http://id.nlm.nih.gov/mesh/2026/D007108
  2. Immune Tolerance. In: Wikipedia. https://en.wikipedia.org/wiki/Immune_tolerance
  3. Immune Tolerance. In: Wikidata. https://www.wikidata.org/wiki/Q1356761