Phenomena and Processes

Immune System Exhaustion

A spectrum of functional deterioration in various lymphocyte populations that is induced by continuous antigenic stimulation. There are overlapping similarities with CELLULAR SENESCENCE; IMMUNOSENESCENCE; T-CELL SENESCENCE; and CLONAL ANERGY.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A spectrum of functional deterioration in various lymphocyte populations that is induced by continuous antigenic stimulation. There are overlapping similarities with CELLULAR SENESCENCE; IMMUNOSENESCENCE; T-CELL SENESCENCE; and CLONAL ANERGY.

MeSH Record

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MeSH Record

Synonyms

8 entry terms
  • Immune Exhaustion
  • B-Cell Exhaustion
  • Lymphocyte Exhaustion
  • Monocyte Exhaustion
  • NK Cell Exhaustion
  • Poly-Lymphocyte Exhaustion
  • B Cell Exhaustion
  • Poly Lymphocyte Exhaustion

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2024

MeSH Hierarchy

Tree Number

  1. G12.590

AMA Style

References

  1. National Library of Medicine. Immune System Exhaustion. Medical Subject Headings (MeSH). 2026. Unique ID D000095842. http://id.nlm.nih.gov/mesh/2026/D000095842
  2. Immune System Exhaustion. In: Wikidata. https://www.wikidata.org/wiki/Q124256074