Structured Summary
Abstract
A tyrosine kinase inhibitor and ANTINEOPLASTIC AGENT that inhibits the BCR-ABL kinase created by chromosome rearrangements in CHRONIC MYELOID LEUKEMIA and ACUTE LYMPHOBLASTIC LEUKEMIA, as well as PDG-derived tyrosine kinases that are overexpressed in gastrointestinal stromal tumors.
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
Drug Class
Pharmacological Action
MeSH Record
Synonyms
16 entry terms
- Imatinib Methanesulfonate
- Mesylate, Imatinib
- Methanesulfonate, Imatinib
- Alpha-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-tolu-p-toluidide
- CGP 57148
- CGP-57148
- CGP57148B
- Gleevec
- Glivec
- Imatinib
- ST 1571
- ST1571
- STI 571
- STI-571
- STI571
- CGP57148
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2016 (1996)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Imatinib Mesylate. Medical Subject Headings (MeSH). 2026. Unique ID D000068877. http://id.nlm.nih.gov/mesh/2026/D000068877
- Imatinib Mesylate. In: Wikidata. https://www.wikidata.org/wiki/Q27114666