Chemicals and Drugs

Icodextrin

A glucan that is structurally related to maltodextrin, with more than 85% of its molecules having molecular weights between 1640 and 45 000 Daltons (Da), and a weight-average molecular weight of about 20 000 Da; it is used in dialysis fluids as an alternative to glucose-based solutions, and to reduce adhesions after gynecological or abdominal surgery. It has also been used as a vehicle for drugs given via the peritoneal cavity.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A glucan that is structurally related to maltodextrin, with more than 85% of its molecules having molecular weights between 1640 and 45 000 Daltons (Da), and a weight-average molecular weight of about 20 000 Da; it is used in dialysis fluids as an alternative to glucose-based solutions, and to reduce adhesions after gynecological or abdominal surgery. It has also been used as a vehicle for drugs given via the peritoneal cavity.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

2 entry terms
  • Extraneal
  • Icodial

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1997)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Icodextrin. Medical Subject Headings (MeSH). 2026. Unique ID D000077607. http://id.nlm.nih.gov/mesh/2026/D000077607
  2. Icodextrin. In: Wikipedia. https://en.wikipedia.org/wiki/Icodextrin
  3. Icodextrin. In: Wikidata. https://www.wikidata.org/wiki/Q5986553