Structured Summary
Abstract
An enzyme that catalyzes the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-CoA. This is a key enzyme in steroid biosynthesis. This enzyme was formerly listed as EC 4.1.3.5.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
11 entry terms
- 3-hydroxy-3-methylglutaryl-coenzyme A synthase
- HMG CoA Synthase
- HMG-CoA synthase
- 3 hydroxy 3 methylglutaryl coenzyme A synthase
- A synthase, 3-hydroxy-3-methylglutaryl-coenzyme
- CoA Synthase, HMG
- Hydroxymethylglutaryl CoA Synthase
- Synthase, HMG CoA
- Synthase, Hydroxymethylglutaryl-CoA
- synthase, 3-hydroxy-3-methylglutaryl-coenzyme A
- synthase, HMG-CoA
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
1991(1975);
MeSH Record
Previous Indexing
- Coenzyme A (1973-1974)
- Glutarates (1973-1974)
- Ketoacid-Lyases (1973-1974)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Hydroxymethylglutaryl-CoA Synthase. Medical Subject Headings (MeSH). 2026. Unique ID D006904. http://id.nlm.nih.gov/mesh/2026/D006904
- Hydroxymethylglutaryl-CoA Synthase. In: Wikipedia. https://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_synthase
- Hydroxymethylglutaryl-CoA Synthase. In: Wikidata. https://www.wikidata.org/wiki/Q409147