Structured Summary
Abstract
A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
Chemical Identity
Chemical Information
- Molecular Formula
- C18H26ClN3O
- Molecular Weight
- 335.9 g/mol
- CAS Registry No.
- 118-42-3
- IUPAC Name
- 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol
- InChIKey
- XXSMGPRMXLTPCZ-UHFFFAOYSA-N
- SMILES
- CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO
- MeSH Unique ID
- D006886
- Source
- PubChem CID 3652
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
Drug Class
Pharmacological Action
MeSH Record
Synonyms
6 entry terms
- Hydroxychlorochin
- Oxychlorochin
- Oxychloroquine
- Hydroxychloroquine Sulfate
- Hydroxychloroquine Sulfate (1:1) Salt
- Plaquenil
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Hydroxychloroquine. Medical Subject Headings (MeSH). 2026. Unique ID D006886. http://id.nlm.nih.gov/mesh/2026/D006886
- Hydroxychloroquine. In: Wikipedia. https://en.wikipedia.org/wiki/Hydroxychloroquine
- Hydroxychloroquine. In: Wikidata. https://www.wikidata.org/wiki/Q421094
- Hydroxychloroquine. In: PubChem Compound. CID 3652. https://pubchem.ncbi.nlm.nih.gov/compound/3652