Chemicals and Drugs

Hydromorphone

An opioid analgesic made from MORPHINE and used mainly as an analgesic. It has a shorter duration of action than morphine.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An opioid analgesic made from MORPHINE and used mainly as an analgesic. It has a shorter duration of action than morphine.

Chemical Identity

Chemical Information

Molecular Formula
C17H19NO3
Molecular Weight
285.34 g/mol
CAS Registry No.
466-99-9
IUPAC Name
(4R,4aR,7aR,12bS)-9-hydroxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
InChIKey
WVLOADHCBXTIJK-YNHQPCIGSA-N
SMILES
CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3C(=O)CC4
MeSH Unique ID
D004091
Source
PubChem CID 5284570

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • Dihydromorphinone
  • Hydromorphon
  • Dilaudid
  • Hydromorphone Hydrochloride
  • Laudacon
  • Palladone

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

do not confuse with entry term DIHYDROMORPHINONE with DIHYDROMORPHINE

MeSH Record

History Note

96; was DIHYDROMORPHINONE 1963-95; DIHYDROMORPHINONE DERIVATIVES was see under DIHYDROMORPHINONE 1975-77, was see under MORPHINANS 1969-74

MeSH Hierarchy

Tree Numbers

  1. D03w.132w.577.249.562.450w
  2. D03w.605.497.607.500w
  3. D03w.633.400.686.607.500w
  4. D04w.615w.723w.795.576.450w

AMA Style

References

  1. National Library of Medicine. Hydromorphone. Medical Subject Headings (MeSH). 2026. Unique ID D004091. http://id.nlm.nih.gov/mesh/2026/D004091
  2. Hydromorphone. In: Wikipedia. https://en.wikipedia.org/wiki/Hydromorphone
  3. Hydromorphone. In: Wikidata. https://www.wikidata.org/wiki/Q303646
  4. Hydromorphone. In: PubChem Compound. CID 5284570. https://pubchem.ncbi.nlm.nih.gov/compound/5284570