Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Hydrogen Deuterium Exchange-Mass Spectrometry

A mass spectrometry method utilizing hydrogen-deuterium exchange kinetics to study conformational and dynamic changes especially of proteins, such as interactions during ligand binding and allosteric effects during catalysis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A mass spectrometry method utilizing hydrogen-deuterium exchange kinetics to study conformational and dynamic changes especially of proteins, such as interactions during ligand binding and allosteric effects during catalysis.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

5 entry terms
  • H-D Exchange Mass Spectrometry
  • HDX-MS
  • H D Exchange Mass Spectrometry
  • HDX MS
  • Hydrogen Deuterium Exchange Mass Spectrometry

MeSH Record

Aspects Covered

10 allowable subheadings

Indexed with the subheadings classification, economics, ethics, history, instrumentation, methods, standards, statistics & numerical data, trends, veterinary.

MeSH Record

History Note

2020

MeSH Record

Previous Indexing

  • Deuterium Exchange Measurement (2003-2019)

MeSH Hierarchy

Tree Numbers

  1. E05.196w.344.500
  2. E05.196w.566w.550

AMA Style

References

  1. National Library of Medicine. Hydrogen Deuterium Exchange-Mass Spectrometry. Medical Subject Headings (MeSH). 2026. Unique ID D000080307. http://id.nlm.nih.gov/mesh/2026/D000080307
  2. Hydrogen Deuterium Exchange-Mass Spectrometry. In: Wikidata. https://www.wikidata.org/wiki/Q107695802