Chemicals and Drugs

Hyaluronic Acid

A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.

Chemical Identity

Chemical Information

Molecular Formula
C28H44N2O23
Molecular Weight
776.6 g/mol
CAS Registry No.
125935-84-4
IUPAC Name
(2S,3S,4S,5R,6R)-6-[(2S,3R,5S,6R)-3-acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
InChIKey
KIUKXJAPPMFGSW-MNSSHETKSA-N
SMILES
CC(=O)N[C@H]1[C@@H](O[C@@H]([C@H](C1O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C(=O)O)O[C@H]3[C@@H](C([C@@H]([C@H](O3)CO)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O)NC(=O)C)O)O)O)CO)O
MeSH Unique ID
D006820
Source
PubChem CID 24759

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

13 entry terms
  • Acid, Hyaluronic
  • Amo Vitrax
  • Amvisc
  • Biolon
  • Etamucine
  • Healon
  • Hyaluronan
  • Hyaluronate Sodium
  • Hyvisc
  • Luronit
  • Sodium Hyaluronate
  • Hyaluronate, Sodium
  • Vitrax, Amo

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2002; for BIOLON use POLYMETHYL METHACRYLATE 1977-2001

MeSH Hierarchy

Tree Number

  1. D09w.698w.373w.475w

MeSH Record

NLM Classification

QU 83

AMA Style

References

  1. National Library of Medicine. Hyaluronic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D006820. http://id.nlm.nih.gov/mesh/2026/D006820
  2. Hyaluronic Acid. In: Wikipedia. https://en.wikipedia.org/wiki/Hyaluronic_acid
  3. Hyaluronic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q337231
  4. Hyaluronic Acid. In: PubChem Compound. CID 24759. https://pubchem.ncbi.nlm.nih.gov/compound/24759