Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Hot Melt Extrusion Technology

Solvent-free method for preparing numerous types of drug delivery systems and dosage forms for active pharmaceutical ingredients that have solubility issues. It involves pumping polymeric materials at temperatures above their glass transition temperature to mix in active pharmaceutical ingredients with or without binders thus forming an amorphous product with an increase in the dissolution profile for the active pharmaceutical ingredients.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Solvent-free method for preparing numerous types of drug delivery systems and dosage forms for active pharmaceutical ingredients that have solubility issues. It involves pumping polymeric materials at temperatures above their glass transition temperature to mix in active pharmaceutical ingredients with or without binders thus forming an amorphous product with an increase in the dissolution profile for the active pharmaceutical ingredients.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

1 entry terms
  • Hot Melt Extrusion

MeSH Record

Aspects Covered

10 allowable subheadings

Indexed with the subheadings classification, economics, ethics, history, instrumentation, methods, standards, statistics & numerical data, trends, veterinary.

MeSH Record

History Note

2020

MeSH Hierarchy

Tree Numbers

  1. E05.916w.840
  2. J01.897w.360w.500
  3. J01.897w.836w.500

AMA Style

References

  1. National Library of Medicine. Hot Melt Extrusion Technology. Medical Subject Headings (MeSH). 2026. Unique ID D000080048. http://id.nlm.nih.gov/mesh/2026/D000080048
  2. Hot Melt Extrusion Technology. In: Wikidata. https://www.wikidata.org/wiki/Q114414119