Structured Summary
Abstract
An enzyme that catalyzes the first step of histidine catabolism, forming UROCANIC ACID and AMMONIA from HISTIDINE. Deficiency of this enzyme is associated with elevated levels of serum histidine and is called histidinemia (AMINO ACID METABOLISM, INBORN ERRORS).
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
9 entry terms
- Histidase
- Histidinase
- Histidine Deaminase
- Histidine alpha-Deaminase
- Ammonia-Lyase, Histidine
- Deaminase, Histidine
- Histidine Ammonia Lyase
- Histidine alpha Deaminase
- alpha-Deaminase, Histidine
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
/defic: consider also histidinemia (AMINO ACID METABOLISM, INBORN ERRORS)
MeSH Record
History Note
98(73)
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AMA Style
References
- National Library of Medicine. Histidine Ammonia-Lyase. Medical Subject Headings (MeSH). 2026. Unique ID D006638. http://id.nlm.nih.gov/mesh/2026/D006638
- Histidine Ammonia-Lyase. In: Wikidata. https://www.wikidata.org/wiki/Q24725629