Chemicals and Drugs

Histamine

An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.

Chemical Identity

Chemical Information

Molecular Formula
C5H9N3
Molecular Weight
111.15 g/mol
CAS Registry No.
51-45-6
IUPAC Name
2-(1H-imidazol-5-yl)ethanamine
InChIKey
NTYJJOPFIAHURM-UHFFFAOYSA-N
SMILES
C1=C(NC=N1)CCN
MeSH Unique ID
D006632
Source
PubChem CID 774

MeSH Record

Classification

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

See Also

MeSH Record

Synonyms

4 entry terms
  • Ceplene
  • Histamine Dihydrochloride
  • Histamine Hydrochloride
  • Peremin

MeSH Record

Aspects Covered

27 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analogs & derivatives, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

/antagonists & inhibitors was ANTIHISTAMINICS 1963-76

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Histamine. Medical Subject Headings (MeSH). 2026. Unique ID D006632. http://id.nlm.nih.gov/mesh/2026/D006632
  2. Histamine. In: Wikipedia. https://en.wikipedia.org/wiki/Histamine
  3. Histamine. In: Wikidata. https://www.wikidata.org/wiki/Q61233
  4. Histamine. In: PubChem Compound. CID 774. https://pubchem.ncbi.nlm.nih.gov/compound/774