Diseases

Hippocampal Sclerosis

Neuronal loss in the hippocampal regions of CA1 and CA4 and less severely CA2 and CA3. Additional loss of hippocampal stratum radiatum, hippocampal atrophy and ASTROGLIOSIS are common. Hippocampal sclerosis is associated with intractable TEMPORAL LOBE EPILEPSY.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Neuronal loss in the hippocampal regions of CA1 and CA4 and less severely CA2 and CA3. Additional loss of hippocampal stratum radiatum, hippocampal atrophy and ASTROGLIOSIS are common. Hippocampal sclerosis is associated with intractable TEMPORAL LOBE EPILEPSY.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

23 entry terms
  • Ammon Horn Sclerosis
  • Ammon Horn Scleroses
  • Hippocampal Scleroses
  • Horn Sclerosis, Ammon
  • Sclerosis, Ammon Horn
  • Sclerosis, Hippocampal
  • CA1 Hippocampal Sclerosis
  • CA4 Hippocampal Sclerosis
  • Endfolium Sclerosis
  • Hippocampal Sclerosis of Aging
  • Mesial Temporal Sclerosis
  • Aging Hippocampal Scleroses
  • Aging Hippocampal Sclerosis
  • CA1 Hippocampal Scleroses
  • CA4 Hippocampal Scleroses
  • Endfolium Scleroses
  • Hippocampal Sclerosis, CA1
  • Hippocampal Sclerosis, CA4
  • Scleroses, Mesial Temporal
  • Sclerosis, CA1 Hippocampal
  • Sclerosis, CA4 Hippocampal
  • Sclerosis, Endfolium
  • Sclerosis, Mesial Temporal

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2023

MeSH Record

Previous Indexing

  • Hippocampus (1975-2022)
  • Sclerosis (1975-2022)

MeSH Hierarchy

Tree Numbers

  1. C10w.500w.507.400.187w
  2. C16w.131w.666w.507.400.187w

AMA Style

References

  1. National Library of Medicine. Hippocampal Sclerosis. Medical Subject Headings (MeSH). 2026. Unique ID D000092223. http://id.nlm.nih.gov/mesh/2026/D000092223
  2. Hippocampal Sclerosis. In: Wikipedia. https://en.wikipedia.org/wiki/Hippocampal_sclerosis
  3. Hippocampal Sclerosis. In: Wikidata. https://www.wikidata.org/wiki/Q4421929