Phenomena and Processes

Hippo Signaling Pathway

A signaling pathway that plays a key role in regulating tissue and organ growth. The name derives from the protein kinase Hippo (Hpo) found in DROSOPHILA; where mutations of the Hpo gene result in tissue overgrowth and the hippopotamus phenotype.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A signaling pathway that plays a key role in regulating tissue and organ growth. The name derives from the protein kinase Hippo (Hpo) found in DROSOPHILA; where mutations of the Hpo gene result in tissue overgrowth and the hippopotamus phenotype.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

4 entry terms
  • Hippo Pathway
  • Hippo Signaling
  • Hippo Signaling Pathways
  • Signaling Pathway, Hippo

MeSH Record

Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2022

MeSH Hierarchy

Tree Numbers

  1. G02.111.820w.200w
  2. G04.835w.300w

AMA Style

References

  1. National Library of Medicine. Hippo Signaling Pathway. Medical Subject Headings (MeSH). 2026. Unique ID D000090683. http://id.nlm.nih.gov/mesh/2026/D000090683
  2. Hippo Signaling Pathway. In: Wikipedia. https://en.wikipedia.org/wiki/Hippo_signaling_pathway
  3. Hippo Signaling Pathway. In: Wikidata. https://www.wikidata.org/wiki/Q5768379