Chemicals and Drugs

Hexachlorophene

A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)

Chemical Identity

Chemical Information

Molecular Formula
C13H6Cl6O2
Molecular Weight
406.9 g/mol
CAS Registry No.
70-30-4
IUPAC Name
3,4,6-trichloro-2-[(2,3,5-trichloro-6-hydroxyphenyl)methyl]phenol
InChIKey
ACGUYXCXAPNIKK-UHFFFAOYSA-N
SMILES
C1=C(C(=C(C(=C1Cl)Cl)CC2=C(C(=CC(=C2Cl)Cl)Cl)O)O)Cl
MeSH Unique ID
D006582
Source
PubChem CID 3598

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

1 entry terms
  • Hexachlorophane

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

QV 233

AMA Style

References

  1. National Library of Medicine. Hexachlorophene. Medical Subject Headings (MeSH). 2026. Unique ID D006582. http://id.nlm.nih.gov/mesh/2026/D006582
  2. Hexachlorophene. In: Wikipedia. https://en.wikipedia.org/wiki/Hexachlorophene
  3. Hexachlorophene. In: Wikidata. https://www.wikidata.org/wiki/Q425362
  4. Hexachlorophene. In: PubChem Compound. CID 3598. https://pubchem.ncbi.nlm.nih.gov/compound/3598