Structured Summary
Abstract
Forms of hepcidin, a cationic amphipathic peptide synthesized in the liver as a prepropeptide which is first processed into prohepcidin and then into the biologically active hepcidin forms, including in human the 20-, 22-, and 25-amino acid residue peptide forms. Hepcidin acts as a homeostatic regulators of iron metabolism and also possesses antimicrobial activity.
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Broader headings
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Drug Class
Pharmacological Action
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See Also
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Synonyms
8 entry terms
- Hepcidin
- Liver-Expressed Antimicrobial Peptide
- Antimicrobial Peptide, Liver-Expressed
- Liver Expressed Antimicrobial Peptide
- Peptide, Liver-Expressed Antimicrobial
- Pro-Hepcidin
- Prohepcidin
- Pro Hepcidin
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Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
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History Note
2014
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Previous Indexing
- Antimicrobial Cationic Peptides (2013)
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Tree Numbers
AMA Style
References
- National Library of Medicine. Hepcidins. Medical Subject Headings (MeSH). 2026. Unique ID D064451. http://id.nlm.nih.gov/mesh/2026/D064451
- Hepcidins. In: Wikidata. https://www.wikidata.org/wiki/Q24741819