Structured Summary
Abstract
An enzyme of the isomerase class that catalyzes the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends. (From Enzyme Nomenclature, 1992) EC 4.2.2.7.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
6 entry terms
- Heparin Eliminase
- Heparinase
- Heparinase I
- Neutralase
- Eliminase, Heparin
- Lyase, Heparin
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
98; use HEPARIN LYASE (NM) 1973-97
MeSH Record
Previous Indexing
- Heparin (1973-1982)
- Lyases (1973-1979)
- Polysaccharide-Lyases (1975-1997)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Heparin Lyase. Medical Subject Headings (MeSH). 2026. Unique ID D019763. http://id.nlm.nih.gov/mesh/2026/D019763
- Heparin Lyase. In: Wikipedia. https://en.wikipedia.org/wiki/Heparin_lyase
- Heparin Lyase. In: Wikidata. https://www.wikidata.org/wiki/Q5731653