Diseases

Hemophilia B

A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in detail, not the holy day.) Historical and clinical features resemble those in classic hemophilia (HEMOPHILIA A), but patients present with fewer symptoms. Severity of bleeding is usually similar in members of a single family. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. Treatment is similar to that for hemophilia A. (From Cecil Textbook of Medicine, 19th ed, p1008)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in detail, not the holy day.) Historical and clinical features resemble those in classic hemophilia (HEMOPHILIA A), but patients present with fewer symptoms. Severity of bleeding is usually similar in members of a single family. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. Treatment is similar to that for hemophilia A. (From Cecil Textbook of Medicine, 19th ed, p1008)

MeSH Record

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Broader headings

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MeSH Record

Synonyms

18 entry terms
  • Christmas Disease
  • Deficiency, Factor IX
  • F9 Deficiency
  • Factor IX Deficiency
  • Haemophilia B
  • Hemophilia B(M)
  • Plasma Thromboplastin Component Deficiency
  • Bs, Hemophilia
  • Deficiencies, F9
  • Deficiencies, Factor IX
  • Deficiency, F9
  • Disease, Christmas
  • F9 Deficiencies
  • Factor IX Deficiencies
  • Haemophilia Bs
  • Hemophilia Bs
  • Hemophilia Bs (M)
  • Hemophilia B Leyden

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

1999(1966)

MeSH Hierarchy

Tree Numbers

  1. C15.378w.100w.100.510w
  2. C15.378w.100w.141.510w
  3. C15.378w.463w.510w
  4. C16w.320w.099.510w
  5. C16w.320w.322.235w

MeSH Record

NLM Classification

WH 325

AMA Style

References

  1. National Library of Medicine. Hemophilia B. Medical Subject Headings (MeSH). 2026. Unique ID D002836. http://id.nlm.nih.gov/mesh/2026/D002836
  2. Hemophilia B. In: Wikipedia. https://en.wikipedia.org/wiki/Haemophilia_B
  3. Hemophilia B. In: Wikidata. https://www.wikidata.org/wiki/Q2562598