Structured Summary
Abstract
A membrane protein and MHC class I antigen. It contains an IMMUNOGLOBULIN C1-SET DOMAIN and interacts with BETA 2-MICROGLOBULIN. It may also regulate the interaction of TRANSFERRIN with the TRANSFERRIN RECEPTOR. Mutations in the HFE gene are associated with cases of FAMILIAL HEMOCHROMATOSIS.
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Classification
Broader headings
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Synonyms
4 entry terms
- HFE Protein
- HLA-H Antigen
- Antigen, HLA-H
- HLA H Antigen
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017
MeSH Record
Previous Indexing
- Histocompatibility Antigens Class I (1997-2016)
- Membrane Proteins (1997-2016)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Hemochromatosis Protein. Medical Subject Headings (MeSH). 2026. Unique ID D000071020. http://id.nlm.nih.gov/mesh/2026/D000071020
- Hemochromatosis Protein. In: Wikidata. https://www.wikidata.org/wiki/Q24773061