Chemicals and Drugs

HMGA1b Protein

An AT-hook motif-containing protein (AT-HOOK MOTIFS) that binds to the minor grove of AT-rich regions of DNA. It is a truncated form of HMGA1a protein that is produced by alternative-splicing of the HMGA1 gene. It may function as an architectural chromatin binding protein that is involved in transcriptional regulation.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An AT-hook motif-containing protein (AT-HOOK MOTIFS) that binds to the minor grove of AT-rich regions of DNA. It is a truncated form of HMGA1a protein that is produced by alternative-splicing of the HMGA1 gene. It may function as an architectural chromatin binding protein that is involved in transcriptional regulation.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • AT-Hook 1b Protein, High Mobility Group
  • HMGY Protein
  • AT Hook 1b Protein, High Mobility Group

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2002; for HMGY PROTEIN use HMGA1B PROTEIN (NM) 1993-2001

MeSH Record

Previous Indexing

  • High Mobility Group Proteins (1993-2001)
  • Transcription Factors (1993-2001)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.260w.312w.750
  2. D12.776w.660w.235.400w.500w.200
  3. D12.776w.664w.235.400w.500w.200

AMA Style

References

  1. National Library of Medicine. HMGA1b Protein. Medical Subject Headings (MeSH). 2026. Unique ID D025742. http://id.nlm.nih.gov/mesh/2026/D025742
  2. HMGA1b Protein. In: Wikidata. https://www.wikidata.org/wiki/Q76517859