Chemicals and Drugs

HMGA1a Protein

An 11-kDa AT-hook motif-containing (AT-HOOK MOTIFS) protein that binds to the minor grove of AT-rich regions of DNA. It is the full-length product of the alternatively-spliced HMGA1 gene and may function as an architectural chromatin binding protein that is involved in transcriptional regulation.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An 11-kDa AT-hook motif-containing (AT-HOOK MOTIFS) protein that binds to the minor grove of AT-rich regions of DNA. It is the full-length product of the alternatively-spliced HMGA1 gene and may function as an architectural chromatin binding protein that is involved in transcriptional regulation.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

11 entry terms
  • AT-Hook 1a Protein, High Mobility Group
  • HMG I-Type Protein
  • HMG I-Y Phosphoprotein
  • HMG-I(Y) Protein
  • HMGI Protein
  • HMGI(Y) Gene Product
  • High Mobility Group I(Y) Protein
  • AT Hook 1a Protein, High Mobility Group
  • HMG I Type Protein
  • HMG I Y Phosphoprotein
  • Phosphoprotein, HMG I-Y

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2002; for HMG I-TYPE PROTEIN use HMGA1A PROTEIN (NM) 1993-2001

MeSH Record

Previous Indexing

  • High Mobility Group Proteins (1993-2001)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. HMGA1a Protein. Medical Subject Headings (MeSH). 2026. Unique ID D025741. http://id.nlm.nih.gov/mesh/2026/D025741
  2. HMGA1a Protein. In: Wikidata. https://www.wikidata.org/wiki/Q21133131