Chemicals and Drugs

HLA DNA Probes

DNA probes specific for the human leukocyte antigen genes, which represent the major histocompatibility determinants in humans. The four known loci are designated as A, B, C, and D. Specific antigens are identified by a locus notation and number, e.g., HLA-A11. The inheritance of certain HLA alleles is associated with increased risk for certain diseases (e.g., insulin-dependent diabetes mellitus).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

DNA probes specific for the human leukocyte antigen genes, which represent the major histocompatibility determinants in humans. The four known loci are designated as A, B, C, and D. Specific antigens are identified by a locus notation and number, e.g., HLA-A11. The inheritance of certain HLA alleles is associated with increased risk for certain diseases (e.g., insulin-dependent diabetes mellitus).

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

29 entry terms
  • DNA Probes, HLA
  • DNA Probes, Histocompatibility Antigen
  • Histocompatibility Antigen DNA Probes
  • Human Leukocyte Antigen DNA Probes
  • Probes, HLA DNA
  • HLA-A DNA Probes
  • HLA-B DNA Probes
  • HLA-C DNA Probes
  • HLA-D DNA Probes
  • HLA-DR DNA Probes
  • HLA-Dw DNA Probes
  • DNA Probes, HLA-A
  • DNA Probes, HLA-B
  • DNA Probes, HLA-C
  • DNA Probes, HLA-D
  • DNA Probes, HLA-DR
  • DNA Probes, HLA-Dw
  • HLA A DNA Probes
  • HLA B DNA Probes
  • HLA C DNA Probes
  • HLA D DNA Probes
  • HLA DR DNA Probes
  • HLA Dw DNA Probes
  • Probes, HLA-A DNA
  • Probes, HLA-B DNA
  • Probes, HLA-C DNA
  • Probes, HLA-D DNA
  • Probes, HLA-DR DNA
  • Probes, HLA-Dw DNA

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

91(89); was see under DNA PROBES 1989-90

MeSH Record

Previous Indexing

  • DNA or specific DNA (1972-1988)
  • HLA Antigens (1974-1988)
  • Nucleic Acid Hybridization (1972-1988)

MeSH Hierarchy

Tree Numbers

  1. D13.444w.600.223.550
  2. D27.505.259.750w.600.223.615
  3. D27.720.470.530w.600.223.615

AMA Style

References

  1. National Library of Medicine. HLA DNA Probes. Medical Subject Headings (MeSH). 2026. Unique ID D015343. http://id.nlm.nih.gov/mesh/2026/D015343
  2. HLA DNA Probes. In: Wikidata. https://www.wikidata.org/wiki/Q50573422