Chemicals and Drugs

HLA-B Antigens

Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable alleles on locus B of the HLA complex, the most polymorphic of all the HLA specificities. Several of these antigens (e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic T lymphocytes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable alleles on locus B of the HLA complex, the most polymorphic of all the HLA specificities. Several of these antigens (e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic T lymphocytes.

MeSH Record

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MeSH Record

Synonyms

7 entry terms
  • Antigens, HLA-B
  • HLA-B
  • HLA-B Antigen
  • Antigen, HLA-B
  • Antigens, HLA B
  • HLA B Antigen
  • HLA B Antigens

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

general; prefer specifics

MeSH Record

History Note

89

MeSH Record

Previous Indexing

  • HLA Antigens (1975-1988)
  • Histocompatibility Antigens (1975-1981)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.489.500
  2. D12.776w.395w.550w.489.500
  3. D12.776w.543w.550w.439.500
  4. D23.050w.301.500.100.500
  5. D23.050w.301.500.450w.380
  6. D23.050w.705.552.100.500
  7. D23.050w.705.552.450w.380

AMA Style

References

  1. National Library of Medicine. HLA-B Antigens. Medical Subject Headings (MeSH). 2026. Unique ID D015235. http://id.nlm.nih.gov/mesh/2026/D015235
  2. HLA-B Antigens. In: Wikidata. https://www.wikidata.org/wiki/Q3782045