Chemicals and Drugs

HLA-A Antigens

Polymorphic class I human histocompatibility (HLA) surface antigens present on almost all nucleated cells. At least 20 antigens have been identified which are encoded by the A locus of multiple alleles on chromosome 6. They serve as targets for T-cell cytolytic responses and are involved with acceptance or rejection of tissue/organ grafts.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Polymorphic class I human histocompatibility (HLA) surface antigens present on almost all nucleated cells. At least 20 antigens have been identified which are encoded by the A locus of multiple alleles on chromosome 6. They serve as targets for T-cell cytolytic responses and are involved with acceptance or rejection of tissue/organ grafts.

MeSH Record

Classification

Broader headings

Narrower headings

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MeSH Record

Synonyms

4 entry terms
  • Antigens, HLA-A
  • HLA-A
  • Antigens, HLA A
  • HLA A Antigens

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

general; prefer specifics

MeSH Record

History Note

89

MeSH Record

Previous Indexing

  • HLA Antigens (1975-1988)
  • Histocompatibility Antigens (1975-1980)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.489.400
  2. D12.776w.395w.550w.489.400
  3. D12.776w.543w.550w.439.400
  4. D23.050w.301.500.100.400
  5. D23.050w.301.500.450w.370
  6. D23.050w.705.552.100.400
  7. D23.050w.705.552.450w.370

AMA Style

References

  1. National Library of Medicine. HLA-A Antigens. Medical Subject Headings (MeSH). 2026. Unique ID D015234. http://id.nlm.nih.gov/mesh/2026/D015234
  2. HLA-A Antigens. In: Wikidata. https://www.wikidata.org/wiki/Q5630036