Chemicals and Drugs

HIV Envelope Protein gp41

Transmembrane envelope protein of the HUMAN IMMUNODEFICIENCY VIRUS which is encoded by the HIV env gene. It has a molecular weight of 41,000 and is glycosylated. The N-terminal part of gp41 is thought to be involved in CELL FUSION with the CD4 ANTIGENS of T4 LYMPHOCYTES, leading to syncytial formation. Gp41 is one of the most common HIV antigens detected by IMMUNOBLOTTING.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Transmembrane envelope protein of the HUMAN IMMUNODEFICIENCY VIRUS which is encoded by the HIV env gene. It has a molecular weight of 41,000 and is glycosylated. The N-terminal part of gp41 is thought to be involved in CELL FUSION with the CD4 ANTIGENS of T4 LYMPHOCYTES, leading to syncytial formation. Gp41 is one of the most common HIV antigens detected by IMMUNOBLOTTING.

MeSH Record

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MeSH Record

Synonyms

6 entry terms
  • Envelope Protein gp41, HIV
  • HIV Transmembrane Protein gp41
  • HTLV-III gp41
  • env Protein gp41, HIV
  • gp41 Envelope Protein, HIV
  • gp41(HIV)

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

90

MeSH Record

Previous Indexing

  • Retroviridae Proteins (1986-1989)
  • Viral Envelope Proteins (1983-1989)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.543w.512w.500.330w
  2. D12.776w.964w.350.520.330w
  3. D12.776w.964w.775.325.164.200w
  4. D12.776w.964w.775.562.500.200w
  5. D12.776w.964w.970w.880.325.164.200w
  6. D12.776w.964w.970w.880.910.330w
  7. D23.050w.327.520.330w

MeSH Record

NLM Classification

WC 503

AMA Style

References

  1. National Library of Medicine. HIV Envelope Protein gp41. Medical Subject Headings (MeSH). 2026. Unique ID D015700. http://id.nlm.nih.gov/mesh/2026/D015700
  2. HIV Envelope Protein gp41. In: Wikipedia. https://en.wikipedia.org/wiki/Gp41
  3. HIV Envelope Protein gp41. In: Wikidata. https://www.wikidata.org/wiki/Q5590520