Chemicals and Drugs

H-Y Antigen

A sex-specific cell surface antigen produced by the sex-determining gene of the Y chromosome in mammals. It causes syngeneic grafts from males to females to be rejected and interacts with somatic elements of the embryologic undifferentiated gonad to produce testicular organogenesis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A sex-specific cell surface antigen produced by the sex-determining gene of the Y chromosome in mammals. It causes syngeneic grafts from males to females to be rejected and interacts with somatic elements of the embryologic undifferentiated gonad to produce testicular organogenesis.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

6 entry terms
  • GA-1 Germ Cell Antigen
  • HY Antigen
  • Antigen, H-Y
  • Antigen, HY
  • GA 1 Germ Cell Antigen
  • H Y Antigen

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

mammals only

MeSH Record

History Note

79

MeSH Record

Previous Indexing

  • Histocompatibility (1968-1972)
  • Histocompatibility Antigens (1973-1978)

MeSH Hierarchy

Tree Numbers

  1. D23.050w.301.500.600w.400w
  2. D23.050w.705.552.600w.400w

AMA Style

References

  1. National Library of Medicine. H-Y Antigen. Medical Subject Headings (MeSH). 2026. Unique ID D006182. http://id.nlm.nih.gov/mesh/2026/D006182
  2. H-Y Antigen. In: Wikipedia. https://en.wikipedia.org/wiki/H-Y_antigen
  3. H-Y Antigen. In: Wikidata. https://www.wikidata.org/wiki/Q5627855