Chemicals and Drugs

H(+)-K(+)-Exchanging ATPase

An enzyme isolated from the GASTRIC MUCOSA that catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions across the cell wall. This enzyme was formerly listed as EC 3.6.1.36.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme isolated from the GASTRIC MUCOSA that catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions across the cell wall. This enzyme was formerly listed as EC 3.6.1.36.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

14 entry terms
  • ATPase, Hydrogen, Potassium
  • Adenosine Triphosphatase, Hydrogen, Potassium
  • Adenosinetriphosphatase, Hydrogen, Potassium
  • Gastric H(+) K(+) ATPase
  • H(+)-K(+)-Transporting ATPase
  • Hydrogen, Potassium ATPase
  • Hydrogen, Potassium, Adenosine Triphosphatase
  • Hydrogen, Potassium, Adenosinetriphosphatase
  • Hydrogen-Potassium-Exchanging ATPase
  • Potassium Hydrogen ATPase
  • ATPase Hydrogen, Potassium
  • ATPase, Hydrogen-Potassium-Exchanging
  • ATPase, Potassium Hydrogen
  • Hydrogen Potassium Exchanging ATPase

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

do not confuse entry term H(+)-K(+)-TRANSPORTING ATPASE with PROTON-TRANSLOCATING ATPASES

MeSH Record

History Note

94; was H(+)-K(+)-TRANSPORTING ATPASE 1993; was POTASSIUM HYDROGEN ATPASE (NM) 1980-92

MeSH Record

Previous Indexing

  • Adenosinetriphosphatase (1980-1992)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.040w.025w.314w.625w
  2. D12.776w.157w.530w.450w.250.875w.500.625w
  3. D12.776w.157w.530w.813w.625w
  4. D12.776w.543w.585w.450w.250.875w.500.625w
  5. D12.776w.543w.585w.813w.625w

AMA Style

References

  1. National Library of Medicine. H(+)-K(+)-Exchanging ATPase. Medical Subject Headings (MeSH). 2026. Unique ID D017506. http://id.nlm.nih.gov/mesh/2026/D017506
  2. H(+)-K(+)-Exchanging ATPase. In: Wikipedia. https://en.wikipedia.org/wiki/Hydrogen_potassium_ATPase
  3. H(+)-K(+)-Exchanging ATPase. In: Wikidata. https://www.wikidata.org/wiki/Q415784