Chemicals and Drugs

Guanosine 5'-O-(3-Thiotriphosphate)

Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes.

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Classification

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MeSH Record

Synonyms

7 entry terms
  • GTP gamma S
  • GTPgammaS
  • Guanosine 5'-(3-O-Thio)Triphosphate
  • Guanosine 5'-(gamma-S)Triphosphate
  • gamma-Thio-GTP
  • gamma S, GTP
  • gamma Thio GTP

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/biosyn /physiol permitted

MeSH Record

History Note

91

MeSH Record

Previous Indexing

  • Guanosine Triphosphate (1972-1990)
  • Thionucleotides (1977-1990)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Guanosine 5'-O-(3-Thiotriphosphate). Medical Subject Headings (MeSH). 2026. Unique ID D016244. http://id.nlm.nih.gov/mesh/2026/D016244
  2. Guanosine 5'-O-(3-Thiotriphosphate). In: Wikidata. https://www.wikidata.org/wiki/Q78315811