Chemicals and Drugs

Growth Differentiation Factor 15

A growth differentiation factor that is secreted in response to cell stress and in response to MACROPHAGE ACTIVATION. In addition growth differentiation factor 15 demonstrates a diverse array of biological properties including the induction of cartilage formation, the inhibition of hematopoietic progenitor proliferation, and the induction of neuronal migration.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A growth differentiation factor that is secreted in response to cell stress and in response to MACROPHAGE ACTIVATION. In addition growth differentiation factor 15 demonstrates a diverse array of biological properties including the induction of cartilage formation, the inhibition of hematopoietic progenitor proliferation, and the induction of neuronal migration.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

4 entry terms
  • GDF-15
  • Macrophage Inhibitory Cytokine 1
  • Prostate Differentiation Factor
  • Differentiation Factor, Prostate

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2009(1997)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.276.374w.305
  2. D12.644w.276.954.300w.915
  3. D12.776w.467.374w.305
  4. D12.776w.467.942.300w.915
  5. D23.529.374w.305
  6. D23.529.942.300w.915

AMA Style

References

  1. National Library of Medicine. Growth Differentiation Factor 15. Medical Subject Headings (MeSH). 2026. Unique ID D055436. http://id.nlm.nih.gov/mesh/2026/D055436
  2. Growth Differentiation Factor 15. In: Wikidata. https://www.wikidata.org/wiki/Q74581