Structured Summary
Abstract
A family of serine endopeptidases found in the SECRETORY GRANULES of LEUKOCYTES such as CYTOTOXIC T-LYMPHOCYTES and NATURAL KILLER CELLS. When secreted into the intercellular space granzymes act to eliminate transformed and virus-infected host cells.
MeSH Record
Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
21 entry terms
- Granzyme
- Cytotoxic Serine Protease B
- Cytotoxic T-Lymphocyte Associated 1 Protein
- Cytotoxic T-Lymphocyte Proteinase 1
- Fragmentin 2
- Granzyme A
- Granzyme B
- Granzyme C
- Granzyme K
- Granzyme M
- Granzyme-3
- Granzyme-Like Protein III
- Hanukah Factor
- NK-Tryptase-2
- Natural Killer Cell Granule Tryptase-2
- Cytotoxic T Lymphocyte Associated 1 Protein
- Cytotoxic T Lymphocyte Proteinase 1
- Granzyme 3
- Granzyme Like Protein III
- NK Tryptase 2
- Natural Killer Cell Granule Tryptase 2
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2007(1986)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Granzymes. Medical Subject Headings (MeSH). 2026. Unique ID D053804. http://id.nlm.nih.gov/mesh/2026/D053804
- Granzymes. In: Wikipedia. https://en.wikipedia.org/wiki/Granzyme
- Granzymes. In: Wikidata. https://www.wikidata.org/wiki/Q425068