Anatomy

Granulosa Cells

Supporting cells for the developing female gamete in the OVARY. They are derived from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the OOCYTE in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the OVUM in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors (RECEPTORS, LH).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Supporting cells for the developing female gamete in the OVARY. They are derived from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the OOCYTE in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the OVUM in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors (RECEPTORS, LH).

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Synonyms

3 entry terms
  • Cell, Granulosa
  • Cells, Granulosa
  • Granulosa Cell

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Aspects Covered

15 allowable subheadings

Indexed with the subheadings chemistry, classification, cytology, drug effects, enzymology, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.

MeSH Record

History Note

78(75); was see under GRAAFIAN FOLLICLE 1975-77

MeSH Hierarchy

Tree Numbers

  1. A05w.360w.319w.114w.630w.535w.200w
  2. A06w.300w.312w.497w.535w.300w
  3. A11w.382.812w
  4. A11w.436.329w

AMA Style

References

  1. National Library of Medicine. Granulosa Cells. Medical Subject Headings (MeSH). 2026. Unique ID D006107. http://id.nlm.nih.gov/mesh/2026/D006107
  2. Granulosa Cells. In: Wikipedia. https://en.wikipedia.org/wiki/Granulosa_cell
  3. Granulosa Cells. In: Wikidata. https://www.wikidata.org/wiki/Q1543282