Chemicals and Drugs

Glycogen Synthase Kinase 3 beta

A glycogen synthase kinase-3 type enzyme that functions in ENERGY METABOLISM; EMBRYONIC DEVELOPMENT; and NEUROGENESIS. It is also involved in PROTEIN BIOSYNTHESIS and regulates cell growth and proliferation as a component of the WNT SIGNALING PATHWAY and other signaling pathways. Certain polymorphisms in the GSK3B gene have been associated with PARKINSON DISEASE; ALZHEIMER DISEASE; and BIPOLAR DISORDER.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A glycogen synthase kinase-3 type enzyme that functions in ENERGY METABOLISM; EMBRYONIC DEVELOPMENT; and NEUROGENESIS. It is also involved in PROTEIN BIOSYNTHESIS and regulates cell growth and proliferation as a component of the WNT SIGNALING PATHWAY and other signaling pathways. Certain polymorphisms in the GSK3B gene have been associated with PARKINSON DISEASE; ALZHEIMER DISEASE; and BIPOLAR DISORDER.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

4 entry terms
  • GSK-3beta
  • GSK3B Protein
  • GSK3beta
  • GSK 3beta

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017 (2002)

MeSH Hierarchy

Tree Numbers

  1. D05.500w.117.875w.500
  2. D08.811w.913w.696w.620.682w.700w.429.500w.500
  3. D08.811w.913w.696w.620.682w.700w.646.625w.500
  4. D12.776w.476.081.875w.500
  5. D12.776w.476.563w.429.500w.500
  6. D12.776w.476.563w.646.625w.500

AMA Style

References

  1. National Library of Medicine. Glycogen Synthase Kinase 3 beta. Medical Subject Headings (MeSH). 2026. Unique ID D000071679. http://id.nlm.nih.gov/mesh/2026/D000071679
  2. Glycogen Synthase Kinase 3 beta. In: Wikidata. https://www.wikidata.org/wiki/Q5514576