Chemicals and Drugs

Glycine Dehydrogenase (Decarboxylating)

A PYRIDOXAL PHOSPHATE dependent enzyme that catalyzes the decarboxylation of GLYCINE with the transfer of an aminomethyl group to the LIPOIC ACID moiety of the GLYCINE DECARBOXYLASE COMPLEX H-PROTEIN. Defects in P-protein are the cause of non-ketotic hyperglycinemia. It is one of four subunits of the glycine decarboxylase complex.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A PYRIDOXAL PHOSPHATE dependent enzyme that catalyzes the decarboxylation of GLYCINE with the transfer of an aminomethyl group to the LIPOIC ACID moiety of the GLYCINE DECARBOXYLASE COMPLEX H-PROTEIN. Defects in P-protein are the cause of non-ketotic hyperglycinemia. It is one of four subunits of the glycine decarboxylase complex.

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Classification

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MeSH Record

Synonyms

10 entry terms
  • Glycine Cleavage System P-Protein
  • Glycine Decarboxylase
  • Glycine Decarboxylase Complex P-Protein
  • P-protein, Glycine Decarboxylase
  • Decarboxylase P-protein, Glycine
  • Decarboxylase, Glycine
  • Glycine Cleavage System P Protein
  • Glycine Decarboxylase Complex P Protein
  • Glycine Decarboxylase P-protein
  • P protein, Glycine Decarboxylase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006

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AMA Style

References

  1. National Library of Medicine. Glycine Dehydrogenase (Decarboxylating). Medical Subject Headings (MeSH). 2026. Unique ID D050841. http://id.nlm.nih.gov/mesh/2026/D050841
  2. Glycine Dehydrogenase (Decarboxylating). In: Wikidata. https://www.wikidata.org/wiki/Q24769827