Chemicals and Drugs

Glutathione Synthase

One of the enzymes active in the gamma-glutamyl cycle. It catalyzes the synthesis of glutathione from gamma-glutamylcysteine and glycine in the presence of ATP with the formation of ADP and orthophosphate. EC 6.3.2.3.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

One of the enzymes active in the gamma-glutamyl cycle. It catalyzes the synthesis of glutathione from gamma-glutamylcysteine and glycine in the presence of ATP with the formation of ADP and orthophosphate. EC 6.3.2.3.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • Glutathione Synthetase
  • Synthase, Glutathione
  • Synthetase, Glutathione

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

98(77)

MeSH Record

Previous Indexing

  • Glutathione (1973-1976)
  • Peptide Synthetases (1973-1976)

MeSH Hierarchy

Tree Number

  1. D08.811w.464w.259.850.500w

AMA Style

References

  1. National Library of Medicine. Glutathione Synthase. Medical Subject Headings (MeSH). 2026. Unique ID D005981. http://id.nlm.nih.gov/mesh/2026/D005981
  2. Glutathione Synthase. In: Wikipedia. https://en.wikipedia.org/wiki/Glutathione_synthetase
  3. Glutathione Synthase. In: Wikidata. https://www.wikidata.org/wiki/Q106950316