Structured Summary
Abstract
One of the most abundant isoenzymes of the glutathione peroxidase family. Located in the cytosol and mitochondria, it catalyzes the reduction of HYDROGEN PEROXIDE to water, functioning to limit the accumulation of hydrogen peroxide and modulating processes that utilize hydrogen peroxide; and also the reduction of other organic hydroperoxides to their corresponding alcohols.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
4 entry terms
- GPX1 Glutathione Peroxidase
- Glutathione Peroxidase 1
- GPX1, Glutathione Peroxidase
- Glutathione Peroxidase, GPX1
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2023 (1999)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Glutathione Peroxidase GPX1. Medical Subject Headings (MeSH). 2026. Unique ID D000094765. http://id.nlm.nih.gov/mesh/2026/D000094765
- Glutathione Peroxidase GPX1. In: Wikidata. https://www.wikidata.org/wiki/Q21157938