Chemicals and Drugs

Glutamate-5-Semialdehyde Dehydrogenase

An NADP+ dependent enzyme that catalyzes the oxidation of L-glutamate 5-semialdehyde to L-glutamyl 5-phosphate. It plays a role in the urea cycle and metabolism of amino groups.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An NADP+ dependent enzyme that catalyzes the oxidation of L-glutamate 5-semialdehyde to L-glutamyl 5-phosphate. It plays a role in the urea cycle and metabolism of amino groups.

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Classification

Broader headings

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MeSH Record

Synonyms

14 entry terms
  • Beta-Glutamylphosphate Reductase
  • Gamma-Glutamylphosphate Reductase
  • Glutamate 5-Semialdehyde Dehydrogenase
  • Glutamate-Semialdehyde Dehydrogenase
  • 5-Semialdehyde Dehydrogenase, Glutamate
  • Beta Glutamylphosphate Reductase
  • Dehydrogenase, Glutamate 5-Semialdehyde
  • Dehydrogenase, Glutamate-5-Semialdehyde
  • Dehydrogenase, Glutamate-Semialdehyde
  • Gamma Glutamylphosphate Reductase
  • Glutamate 5 Semialdehyde Dehydrogenase
  • Glutamate Semialdehyde Dehydrogenase
  • Reductase, Beta-Glutamylphosphate
  • Reductase, Gamma-Glutamylphosphate

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1978)

MeSH Record

Previous Indexing

  • Aldehyde Oxidoreductases (1978-2005)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Glutamate-5-Semialdehyde Dehydrogenase. Medical Subject Headings (MeSH). 2026. Unique ID D050698. http://id.nlm.nih.gov/mesh/2026/D050698
  2. Glutamate-5-Semialdehyde Dehydrogenase. In: Wikipedia. https://en.wikipedia.org/wiki/Glutamate-5-semialdehyde_dehydrogenase
  3. Glutamate-5-Semialdehyde Dehydrogenase. In: Wikidata. https://www.wikidata.org/wiki/Q3772530